Referring Providers: Partner with Southbury Neuropathy for Patient Care

We’re not here to replace you as their doctor. We’re here to be the supportive service you recommend to your patients.

Quick Answer

Physiologic Insulin Resensitization (PIR) is an advanced treatment offered by the Connecticut Diabetes Center that utilizes precision-timed pulses of rapid-acting insulin to restore healthier insulin signaling and reduce insulin resistance in diabetic patients. This method aims to improve underlying metabolic dysfunction, leading to more efficient glucose utilization and enhanced cellular energy metabolism. The Connecticut Diabetes Center reports a 95% success rate in achieving significant improvement or elimination of diabetic neuropathy symptoms with PIR, based on a Schull Institute study. Patients often experience benefits beyond glycemic control, including improved kidney function, reduced medication needs, and an overall enhanced quality of life.

ACCOMPLISHMENTS

  • 10+ Years Research, Development, & Data Capture
  • 400,000+ Safe and Effective Infusions
  • 200+ Provider Locations Licensed
  • 10+ University Collaborations
  • 2 Issued Patents & 1 Pending Patent
  • 11 Peer-Reviewed Publications

95% Success Rate in Achieving Significant Improvement or Elimination of Diabetic Neuropathy Symptoms*

*Schull Institute Study Insulin Infusion Therapy on Diabetic Complications (Oct 27, 2015) Retrospective, observational study (n=60) reported:

REFERRING PHYSICIANS
& PROVIDERS

Let’s help your patients together! 

A message to Physicians from Dr Maria Henry

Dr. Maria Henry, MD
PIR Medical Supervisor
Diabetes & Neuropathy Restoration Center

PIR PATIENTS REPORT:

  • Reduce Medications
  • Improved Blood Sugar Control
  • Improved A1C
  • Improved Neuropathy Pain
  • Improved Heart Health
  • Improved Energy
  • Improved Memory
  • Improved Eyesight
  • Improved Sexual function
  • Improved Blood Pressure
  • Improved Mood
  • Improved Sleep
  • Improved Kidney Function
  • Improved Fatty Liver
  • IMPROVED QUALITY OF LIFE!

OPEN LETTER TO PHYSICIANS

Dear Colleagues,

Throughout my career as an Internal Medicine physician, I have cared for countless individuals living with diabetes and its many systemic complications. Despite significant advances in diabetes management, many patients continue to experience progressive neuropathy, declining renal function, fatigue, vascular disease, and other complications—even when blood glucose levels appear reasonably controlled. This is why I was excited to bring Physiologic Insulin Resensitization (PIR) to Connecticut nearly three years ago.

Since opening our program, we have administered more than 2,500 PIR treatments, and I have been extremely pleased with the consistency of the clinical outcomes we have observed. While individual results naturally vary, many patients experience improvements that extend well beyond glycemic control. PIR utilizes precision-timed pulses of rapid-acting insulin delivered in a physiologic pattern designed to more closely mimic normal pancreatic insulin secretion.

Rather than using insulin solely as a glucose-lowering medication, this approach seeks to restore healthier insulin signaling by improving insulin receptor responsiveness and reducing insulin resistance. As insulin sensitivity improves, glucose is utilized more efficiently by cells, supporting normal mitochondrial oxidative phosphorylation and cellular ATP production. Improved cellular energy metabolism may enhance tissue function, repair, and overall metabolic health throughout the body.

In our clinical experience, PIR appears to provide its greatest benefit in patients with diabetic peripheral neuropathy and diabetes-related chronic kidney disease, while many patients also report improvements in energy, functional capacity, and overall quality of life. These observations reinforce an important concept: successful diabetes management should focus on more than blood sugar alone. Addressing insulin resistance may help improve the underlying metabolic dysfunction that contributes to many long-term diabetic complications.

PIR is delivered using an FDA-cleared infusion device together with rapid-acting insulin administered according to a patented treatment protocol. It is intended to complement—not replace—a patient’s existing diabetes management plan. We work collaboratively with each patient’s primary care physician, endocrinologist, nephrologist, and other specialists to help optimize overall diabetic health. As physicians, our shared goal is to reduce the burden of diabetes and improve our patients; long term outcomes. I believe Physiologic Insulin Resensitization represents a valuable adjunctive therapy for appropriately selected patients, and I welcome the opportunity to discuss our program or collaborate in the care of your patients.

Respectfully,

Maria Henry, MD
PIR Medical Supervisor
Diabetes & Neuropathy Restoration Center

Where can physicians refer diabetic neuropathy patients?

As specialists in peripheral neuropathy for the past 8 years, with a proven reputation as the go-to clinic for managing neuropathy pain and numbness, we understand the challenge you face in finding a reliable referral option for diabetic neuropathy cases. As a trusted referral partner for many local physicians, you now have a dependable clinic to refer your neuropathy patients to.

PIR boasts a 95% success rate in delivering significant improvements in neuropathy pain and numbness. The results speak for themselves so give us a try!

What is the reality of traditional CKD treatments?

With traditional management of chronic kidney disease, STABILIZATION (not improvement) is often the goal and considered a successful outcome.

Because CKD is generally progressive, improvement in all stages is relatively uncommon, and many patients continue to experience gradual decline over time.

A DIFFERENT OUTCOME
IS POSSIBLE WITH P.I.R

In contrast, clinical studies of Physiologic Insulin Resensitization (PIR) have demonstrated:

  • Up to 43% improvement in CKD stage
  • Approximately 50% remained stable
  • Less than 10% experienced further progression.

These amazing results are based on published clinical research.
Click here to review and download the studies.

CKD Recovery

PIR Effects on CKD

Kidney Disease

How do PIR treatment results for CKD compare to traditional management?

Clinical studies (of all stages 3A-5) show that with traditional CKD management, the goal is to slow decline, and improvement is rare (based on published data in moderate-to-advanced CKD). In contrast, with P.I.R. treatment, clinical studies show better outcomes, with results from Physiologic Insulin Resensitization (PIR) demonstrating improvement. Clinically, improvement from stage 4 to stage 3, 2 or 1 has been observed in some patients within 12 months of PIR treatment.

WITH TRADITIONAL CKD MANAGEMENT*

Goal is to slow decline. Improvement is rare.

*Based on published data in
moderate-to-advanced CKD.

WITH P.I.R
TREATMENT*

Clinical studies show better outcomes.

*Results from clinical studies of
Physiologic Insulin Resensitization (PIR).

CLINICAL OBSERVATION:

In clinical practice, improvement from stage 4 to stage 3, 2 or 1 has been observed in some patients within 12 months of PIR treatment.

What are P.I.R. patient testimonials and experiences?

These patient testimonials are from Diabetes Relief Centers in Florida. Same P.I.R. Treatment.
(we’ll have our own testimonials soon)

“Exceeded my expectations. Pain in my feet is gone!”

Don | Type 1 Diabetic

“My diabetes & blood pressure are back to normal”

Dennis | Diabetic

“My A1C is the lowest it’s ever been in 40 years!”

Faye | Diabetic